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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 19.39
Human Site: S1106 Identified Species: 28.44
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S1106 C G C R K Q K S D C G V D C S
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1099 C G C R K Q K S D C G V D C S
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S1106 C G C R K Q K S D C G V D C C
Dog Lupus familis XP_549061 1234 139874 S1106 C G C R R Q K S D C G M D C S
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S1104 C G C R K Q K S D C N V S C S
Rat Rattus norvegicus Q7M6Z5 1394 158861 D1188 L H H F K D Q D G E G I I E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 G1096 R C G N R Q C G C R K Q K V G
Frog Xenopus laevis Q91784 1226 138905 T1100 K M C G C R K T K Q N C S D D
Zebra Danio Brachydanio rerio Q58G59 1363 154819 V1229 L R E M C G P V N L T G E Q C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 N658 S L R F K S E N I V N Y E L E
Honey Bee Apis mellifera XP_395595 1064 123475 P934 D D D I E K D P D W K R T P L
Nematode Worm Caenorhab. elegans P46873 699 78760 N573 I K K E A V W N E D E S R W I
Sea Urchin Strong. purpuratus P46872 699 78679 L573 Q R E M E A L L E N V R E L S
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 A920 K L R E H A L A V A L A T A A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 S1055 P S D D A V K S D V C C C T C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 R802 E Q L T Q V Q R Q L V E Q N S
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 13.3 N.A. N.A. 6.6 13.3 0 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 33.3 N.A. N.A. 13.3 26.6 13.3 N.A. 26.6 20 13.3 26.6
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 0 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 13.3 N.A. N.A. 20 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 13 0 7 0 7 0 7 0 7 7 % A
% Cys: 32 7 38 0 13 0 7 0 7 32 7 13 7 32 19 % C
% Asp: 7 7 13 7 0 7 7 7 44 7 0 0 25 7 7 % D
% Glu: 7 0 13 13 13 0 7 0 13 7 7 7 19 7 7 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 32 7 7 0 7 0 7 7 0 32 7 0 0 7 % G
% His: 0 7 7 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 7 0 0 0 0 7 0 0 7 7 0 7 % I
% Lys: 13 7 7 0 38 7 44 0 7 0 13 0 7 0 0 % K
% Leu: 13 13 7 0 0 0 13 7 0 13 7 0 0 13 7 % L
% Met: 0 7 0 13 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 13 7 7 19 0 0 7 0 % N
% Pro: 7 0 0 0 0 0 7 7 0 0 0 0 0 7 0 % P
% Gln: 7 7 0 0 7 38 13 0 7 7 0 7 7 7 0 % Q
% Arg: 7 13 13 32 13 7 0 7 0 7 0 13 7 0 0 % R
% Ser: 7 7 0 0 0 7 0 38 0 0 0 7 13 0 38 % S
% Thr: 0 0 0 7 0 0 0 7 0 0 7 0 13 7 7 % T
% Val: 0 0 0 0 0 19 0 7 7 13 13 25 0 7 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 7 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _